Innovative Research Award
Yuta Maruki — National Cancer Center Hospital, Tokyo, Japan
Yuta Maruki is a physician and clinical researcher at the National Cancer Center Hospital in Tokyo, Japan, whose documented work focuses on hepatobiliary and pancreatic oncology. His research and publications encompass biliary tract cancer, molecular oncology, endoscopic treatment, genomic profiling, procedural sedation, and clinically oriented cancer research. [1]
Abstract
Yuta Maruki is a physician and clinical researcher at the National Cancer Center Hospital in Tokyo, Japan, working in hepatobiliary and pancreatic oncology. His published research addresses biliary tract cancer, FGFR2 rearrangements, endoscopic management, pancreatic cancer genomic profiling, sedation during therapeutic endoscopy, and treatment strategies for hepatocellular carcinoma. His publication record includes prospective observational research, technical endoscopy studies, clinical investigations, and contemporary molecular oncology work. These areas connect translational cancer biology with practical diagnostic and therapeutic care, providing a documented scholarly profile relevant to an Innovative Research Award consideration within medicine and health sciences through multidisciplinary research and care delivery.
Keywords
Biliary tract cancer, cholangiocarcinoma, FGFR2 rearrangements, molecular oncology, genomic profiling, pancreatic cancer, endoscopic ultrasound, biliary drainage, malignant biliary strictures, propofol sedation, therapeutic endoscopy, hepatocellular carcinoma, pharmacological downstaging, precision oncology, biomarker analysis, clinical trials, translational cancer research, and hepatobiliary oncology. molecular diagnostics and precision therapeutic approaches
Introduction
Yuta Maruki’s research profile is situated within hepatobiliary and pancreatic oncology, where molecular characterization and interventional endoscopy intersect with clinical decision making. His studies examine relevant questions involving biliary tract malignancies, pancreatic cancer, and therapeutic procedures. The work reflects collaboration across oncology, pathology, genomics, gastroenterology, and clinical research in Japan. [2]
Research Profile
Yuta Maruki is identified by the National Cancer Center Hospital as an attending physician specializing in hepatobiliary and pancreatic disease, with involvement in clinical trials and research. His institutional profile also describes gastrointestinal endoscopic practice, including gastroscopy and endoscopic retrograde cholangiopancreatography. His documented publications span molecular oncology and therapeutic endoscopy. [2]
Research Contributions
Yuta Maruki’s publications address connected research themes. The PRELUDE study investigated FGFR2 rearrangements in advanced or recurrent biliary tract carcinoma, while later work examined molecular features of cholangiocarcinoma and treatment. Other studies address endoscopic drainage, genomic tissue acquisition, propofol sedation, and pharmacological downstaging, illustrating a broad research portfolio in oncology. [3]
Publications
Yuta Maruki has published on FGFR2 rearrangements in biliary tract carcinoma, endoscopic drainage of malignant biliary strictures, propofol sedation during biliary and pancreatic procedures, genomic profiling of unresectable pancreatic cancer, and pharmacological downstaging in hepatocellular carcinoma. Recent work also includes molecular classification and treatment experience involving FGFR-directed therapy in cholangiocarcinoma. [3] [4]
Research Impact
Yuta Maruki’s research impact can be described through the relevance and continuity of his publication themes than through unsupported claims. His studies contribute evidence concerning molecular testing, endoscopic techniques, genomic profiling, procedural safety, and treatment selection. Citation metrics supplied for this profile indicate 452 citations and an h-index of 11. [3]
Award Suitability
Yuta Maruki’s documented research record provides evidence-based areas for consideration in an Innovative Research Award context, including translational oncology, molecular characterization of biliary cancers, therapeutic endoscopy, and clinically oriented cancer research. His publications demonstrate sustained engagement with multidisciplinary questions connecting laboratory-informed biomarkers, diagnostic procedures, treatment strategies, and patient-focused clinical practice. [4]
Conclusion
Yuta Maruki’s profile combines specialist clinical practice with research in hepatobiliary and pancreatic oncology. His publications address molecular alterations, cancer diagnostics, endoscopic interventions, procedural safety, and therapeutic strategies. The available institutional and publication records provide a factual basis for describing his research trajectory and relevance to medicine and health sciences. [2]
External Links
References
- National Cancer Center Hospital. Yuta Maruki — Department of Hepatobiliary and Pancreatic Oncology.
https://phase1-oncol.ncc.go.jp/en/members/yuta-maruki/
- Maruki, Y., Morizane, C., Arai, Y., et al. (2021). Molecular detection and clinicopathological characteristics of advanced/recurrent biliary tract carcinomas harboring the FGFR2 rearrangements: a prospective observational study (PRELUDE Study). Journal of Gastroenterology.
https://doi.org/10.1007/s00535-020-01735-2
- Maruki, Y., Hijioka, S., Yagi, S., et al. (2025). Sedative effects of propofol and risk factors for excessive sedation in the endoscopic treatment of biliary and pancreatic diseases. DEN Open, 5(1), e417.
https://doi.org/10.1002/deo2.417
- Maruki, Y., Yatabe, Y., Mizoguchi, C., et al. (2026). FGFR2 Fusions or Rearrangements in Young Intrahepatic and Perihilar Cholangiocarcinoma Patients: Key Genetic Insights From a Pan-Asian Study. Hepatology Research.
https://doi.org/10.1111/hepr.70031
- Maruki, Y., Morizane, C., et al. (2025). First Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma with Tasurgratinib Following Regulatory Approval: A Case Report from Clinical Practice. International Journal of Molecular Sciences.
https://doi.org/10.3390/ijms26125586