Associate Researcher, Associate Chief Physician at XiangyaS chool of Stomatology (Xiangya Stomatological Hospital), Central South University, Changsha, Hunan, China,China
Dr. Zhiyuan Deng is an accomplished Associate Researcher and Associate Chief Physician at the Xiangya School of Stomatology, Central South University, Changsha, China. With a strong background in oral and maxillofacial surgery, his research focuses on oral cancer, precancerous lesions, and advanced treatment methods. He has spearheaded numerous high-impact projects, with a particular emphasis on the molecular mechanisms of oral submucous fibrosis and oral squamous cell carcinoma. 🏥
Publication Profile
Scopus
Early Academic Pursuits 🎓
Dr. Zhiyuan Deng pursued his PhD in Oral Plastic Surgery and Cosmetology from Central South University (CSU) in 2017, where he laid the foundation for his extensive research career. His academic journey is grounded in the study of oral health, with a focus on oral and maxillofacial surgery. After completing his doctoral studies, Dr. Deng continued his work as an assistant researcher and associate chief physician at Xiangya School of Stomatology, CSU, where he began to explore groundbreaking areas in oral submucous fibrosis and oral cancer.
Professional Endeavors 💼
Dr. Deng currently serves as an Associate Researcher and Associate Chief Physician in the Department of Oral and Maxillofacial Surgery at Xiangya Stomatological Hospital, Central South University, China. With over seven years of experience, he has gained proficiency in performing complex surgeries, especially in reconstructive and plastic surgery for maxillofacial conditions. Dr. Deng has also led several significant research projects, most notably investigating the role of lncRNA ANRIL/miR-378/PEBP1 signaling in oral submucous fibrosis.
Contributions and Research Focus 🔬
Dr. Deng’s research is focused on the clinical and basic science of oral precancerous lesions and oral cancer, including their molecular mechanisms and regenerative treatments. His work on stem cell activation and regenerative therapies has made valuable contributions to the field of maxillofacial reconstruction. He is currently leading multiple research projects, including grants from the National Natural Science Foundation of China, where his work aims to explore the mechanisms of signaling axes in oral diseases, especially oral submucous fibrosis and squamous cell carcinoma.
Accolades and Recognition 🏆
Dr. Deng has been recognized for his innovative contributions to oral and maxillofacial surgery. His academic achievements include publishing numerous impactful papers in well-regarded journals such as Oral Disease, Cancer Gene Therapy, and Computers in Biology and Medicine. He has also contributed as an editor for multiple books focused on oral health and clinical practice. With an h-index of 5 in SCI citations, Dr. Deng continues to be a prominent figure in his field, earning both national and international recognition.
Impact and Influence 🌍
Dr. Deng’s work has significantly advanced the understanding of oral cancer and regenerative medicine, especially in the context of oral submucous fibrosis. His contributions to the development of biomarkers for early detection and prognosis of oral squamous cell carcinoma are shaping the future of diagnostic and therapeutic approaches. Through his research collaborations with top research centers and his leadership in groundbreaking projects, Dr. Deng’s influence extends beyond clinical practice, impacting the global oral health community.
Legacy and Future Contributions 🔮
Looking ahead, Dr. Deng aims to continue his pioneering research in oral cancer and regenerative medicine. His ongoing research projects are poised to provide further insights into the molecular mechanisms behind oral cancer and potential therapeutic strategies. With an eye on future advancements in stem cell therapies and innovative treatment modalities, Dr. Deng’s work will likely continue to inspire and guide future generations of oral health professionals.
Publications 📚
- “The Investigation of Nfκb Inhibitors to Block Cell Proliferation in OSCC Cell Lines”
Current Medicinal Chemistry, 2024 (Early Access)
- “Identification of Cuproptosis-Related LncRNAs with the Significance in Prognosis and Immunotherapy of Oral Squamous Cell Carcinoma”
Computers in Biology and Medicine, 2024
- “Fibroblast Activating Protein Promotes the Proliferation, Migration, and Activation of Fibroblasts in Oral Submucous Fibrosis”
Oral Disease, 2023
“Mitogen-Activated Protein Kinase Signaling Pathway in Oral Cancer”
Oncology Letters, 2018
- “Research on miRNA-195 and Target Gene CDK6 in Oral Verrucous Carcinoma”
Cancer Gene Therapy, 2017
“Anterolateral Thigh Flap for Reconstruction of Defects after En Bloc Resection of Buccal Cancer: A Retrospective Study of 23 Cases”
Shanghai Journal of Stomatology, 2017
“LRIG1 Expression and Its Possible Suppressor Role in Oral Verrucous Carcinoma”
Journal of Practical Stomatology, 2017
- “Investigation of the Association Between miR-181b, Bcl-2, and LRIG1 in Oral Verrucous Carcinoma”
Molecular Medicine Reports, 2016
- “An Adaptive Immune Response Driven by Mature, Antigen Experienced T and B Cells within the Microenvironment of Oral Squamous Cell Carcinoma”
International Journal of Cancer, 2016
- “Circadian Clock Components RORα and Bmal1 Mediate the Anti-Proliferative Effect of MLN4924 in Osteosarcoma Cells”
Oncotarget, 2016